" Northern (Frankia) and Eastern France (Bugundia) have the merit to have created Peugeot, Renault, Air Liquide, Citroen, Michelin, langue d´Oil, Paris, in brief: French entrepreneurship"
What "langue d'oil" has to do with being entrepreuneuship?
PS: Michelin is originated and always have been over-centralized in Clermont-ferrand, Auvergne, in the southern Half of France, in a region traditionally Occitan-speaking. At least you could find exemples that fit with you point...
Citroen, Renault, etc. have always being bases in Paris the capital. A the attractive point of France it is not surprising that it developped a lot of the most innovative people. Outside of Paris most of the north of France not more industrial/economically developped/densily populated as is for exemple the benelux or Germany.
That has nothing to see with a "northern culture (supposed to be more technic/scientific)" vs "southern/mediterranean" culture (supposed to be less economically and scientifically developped). This schema might work more of less in Italy, not definitly not in France.
We can see the map of human densities (in western Europe it is generally linked with industrialness and strong economies (appart of the old-heavy industries in Nord-pas-de-Calais or Wallonia)
http://www.insee.fr/fr/insee_regions/centre/publi/img/cart2_europe2008.png
Well, northern regione like Champagne, Burgondy, parts of Lorraine, Picardy, are among the less densily populated regions of France, and much below the human density of the very densily populated countries of the "northern core" of germanic Europe that are Benelux, Germany or England...
Economically speaking Paris is the only strong area of northern France, it is separated to the economic core of Europe (the so-called "bannane bleue", which pass by Benelux and Germany) by poor regions (one rural (Picardy), the other more more industrial (Nord-pas-de Calais).
http://www.insee.fr/fr/insee_regions/centre/publi/img/cart3_europe2008.png
" and born Louis Pasteur, Pierre Curie"
The brothers Montgolfiers (who invented flying balloons) are born in Ardèche, in the south-east.
The brothers Lumière invented and developped cinema in Lyon.
Clément Ader, pionner of aviation (before wrigth brothers), is from Toulouse. Curiously Toulouse is still the center of Aeronautical industry, known mainly for huge Airbus complex, but aslo mainy other companies.
etc.
" Isn´t Mediterranian culture more based on vine, access to Mediterranian sea, salt and sunny weather? "
You have a very "cliché" vision of mediterranean, a quite tipically northern European point of view.
Are you speaking about "culture" or "economy"?
well; like northern half of France, the southern half of France's economy is based on services (as many places in the north are), high-tech (like parts of the north-west), tourism (like many places in the north are), wine (like many places in the north are; Champagne, Burgondy), etc. I don't see the ecomically opposition you want to see; In Italy it might maybe be true, in France no.
If you want to find an economic opposition in France, it is between regions of big cities (Paris, Lyon, Marseille, Toulouse) and more rural ones (Champagne, Auvergne, Burgondy, Limousin, Picardy, etc), not north-south.